Ruling out Cystic Fibrosis (CF) in a Pediatric Patient – Examination in 0.56 Seconds
SOMATOM Definition Flash Scanning
*Sedat Alibek, MD; *Michael Lell, MD; **Gundula Staatz, MD | 2009-10-05
* Institute of Radiology, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany
** Section Pediatric Radiology, Institute of Radiology, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany
Andreas Blaha; Business Unit CT, Siemens Healthcare, Forchheim, Germany
This 10-year-old patient has a known allergic asthma disease. Due to recurrent dyspnea conventional chest x-ray imaging was performed. Findings were described as acute and chronic inflammatory changes of the lung tissue. Due to clinical symptoms consistent with those of cystic fibrosis, a standard sweat test was performed (It measuring the concentration of salt in a person’s sweat) indicating elevated values. Conventional chest x-ray examinations did not show clear signs of infiltrations but a rule-out was also not possible.
The patient was referred to the pediatric hospital at the University of Erlangen. Radiologists decided not to do further x-ray exams, but an ultra-low-dose CT scan was ordered for diagnostic information with maximum patient safety.
With the sub-second, 1mSv scan, all kinds of acute and chronic pulmonary tissue changes such as inflammatory changes as well as specific findings of cystic fibrosis such as bronchiectasis, mucoid impactions and necrotic changes could be ruled out. The fast scan time of only 0.56 seconds did not require any sedation of the young patient, who was cooperative.
After this CT scan the patient could be discharged and no further work-up or follow-up was necessary.
The high resolution, non-contrast-enhanced CT examination was performed utilizing only 1 mSv of effective dose. The scan reliably excluded specific findings indicative of cystic fibrosis, thereby indicating a prolonged life expectancy for the patient.
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